Histone antibody

Catalog No. ABIN7127877

The Rabbit Polyclonal anti-Histone antibody is suitable to detect Histone in samples from Human. It has been validated for WB, IP, ELISA, IF and ChIP.

Quick Overview for Histone antibody (ABIN7127877)

Target: Histone

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)

Product Details

Purpose: Histone H4R3me2a Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antigen Affinity Purified

Immunogen: A synthetic methylated peptide corresponding to residues surrounding Arg3 of Human histone H4

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Histone

Background:

Background:

 Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element.

Aliases: H3t; H3.4; H3/g; H3FT;