SERPINA7 antibody

Catalog No. ABIN7128011

Product Details anti-SERPINA7 Antibody

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINA7 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen affinity purification

Immunogen: Full length fusion protein

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SERPINA7

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Alternative Name: SERPINA7 (SERPINA7 Products)

Synonyms: C730040N12Rik antibody, Tbg antibody, TBG antibody, THYROXINE-BINDING GLOBULIN antibody, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 antibody, serpin family A member 7 antibody, Serpina7 antibody, SERPINA7 antibody

Background:

Background: There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

Aliases: Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 7 antibody, Serpin A7 antibody, Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 7 antibody, Serpin peptidase inhibitor, clade A, member 7 antibody, Serpina7 antibody, T4 binding globulin antibody, TBG antibody, TBG, serum antibody, THBG_HUMAN antibody, Thyroxin binding globulin antibody, Thyroxine binding globulin antibody, Thyroxine-binding globulin antibody, Thyroxine-binding globulin od serum antibody

UniProt: P05543

Pathways: Hormone Transport