AADACL2 antibody
Quick Overview for AADACL2 antibody (ABIN7128109)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Purpose
- AADACL2 Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Fusion protein of Human AADACL2
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- AADACL2 (Arylacetamide Deacetylase-Like 2 (AADACL2))
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Alternative Name
- AADACL2
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Background
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Background: AADAC is a 45 kDa membrane-associated hydrolase highly expressed in the human liver that has been implicated in the hydrolysis of arylacetamide xenobiotics including flutamide and phenacetin.556-560AADAC is highly homologous to several related lipases, AADACL1, 2, and 4, the latter two of which remain completely unannotated. Overexpression of AADAC in a rat hepatoma cell line produces changes in cellular TG levels, apoplipoprotein B secretion, and fatty acid oxidation, but the mechanism for these effects remains unclear.561 Candidate endogenous substrates, selective inhibitors, or knockout mice have not, to our knowledge, been described for AADAC or the related enzymes AADACL2 and AADACL4.
Aliases: AADACL2Arylacetamide deacetylase-like 2 antibody, EC 3.1.1.- antibody
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UniProt
- Q6P093
Target
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