MYLK2 antibody

Catalog No. ABIN7130325

The Rabbit Polyclonal anti-MYLK2 antibody has been validated for WB and ELISA. It is suitable to detect MYLK2 in samples from Human.

Quick Overview for MYLK2 antibody (ABIN7130325)

Target: MYLK2 (Myosin Light Chain Kinase 2 (MYLK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYLK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MYLK2 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human MYLK2

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, WB:1:200-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MYLK2

Target: MYLK2 (Myosin Light Chain Kinase 2 (MYLK2))

Alternative Name: MYLK2

Background:

Background: This gene encodes a myosin light chain kinase, a calcium / calmodulin dependent enzyme, that is exclusively expressed in adult skeletal muscle. The MYLK2 gene expresses skMLCK more prevalently in fast twitch muscle fibers as compared to slow twitch muscle fibers. Calmodulin is composed of two terminal domains (N,C) each containing two E-F hand motifs that bind to Ca2+. Upon saturation of Ca2+, Calmodulin undergoes a conformation change allowing it to bind with a target protein such as skMLCK.

Aliases: KMLC antibody, MLCK antibody, MLCK, skeletal/cardiac antibody, MLCK2 antibody, MYLK 2 antibody, MYLK2 antibody, MYLK2_HUMAN antibody, Myosin light chain kinase 2 antibody, Myosin light chain kinase 2 skeletal muscle antibody, Myosin light chain kinase 2 skeletal/cardiac muscle antibody, MYOSIN LIGHT POLYPEPTIDE KINASE antibody, Myosin light polypeptide kinase, skeletal/cardiac antibody, Skeletal muscle myosin light chain kinase antibody, Skeletal myosin light chain kinase antibody, skeletal/cardiac muscle antibody, skMLCK antibody

UniProt: Q9H1R3

Pathways: Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation