Olfactomedin 3 antibody
Quick Overview for Olfactomedin 3 antibody (ABIN7130495)
Target
See all Olfactomedin 3 (OLFM3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Mouse, Rat
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Purification
- Antigen affinity purification
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Immunogen
- Fusion protein of Human OLFM3
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Isotype
- IgG
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Application Notes
- ELISA:1:1000-1:2000, WB:1:200-1:1000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Olfactomedin 3 (OLFM3)
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Alternative Name
- OLFM3
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Background
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Background: OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.
Aliases: OLFM3 antibody, NOE3 antibody, UNQ1924/PRO4399 antibody, Noelin-3 antibody, Olfactomedin-3 antibody, Optimedin antibody
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UniProt
- Q96PB7
Target
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