OPTN antibody

Catalog No. ABIN7130502

The Rabbit Polyclonal anti-OPTN antibody has been validated for IHC and ELISA. It is suitable to detect OPTN in samples from Human.

Quick Overview for OPTN antibody (ABIN7130502)

Target: OPTN (Optineurin (OPTN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPTN antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-OPTN Antibody

Purpose: OPTN Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human OPTN

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for OPTN

Target: OPTN (Optineurin (OPTN))

Alternative Name: OPTN

Background:

Background: This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.

Aliases: 14.7K interacting protein antibody, Ag9 C5 antibody, ALS12 antibody, E3 14.7K interacting protein antibody, E3-14.7K-interacting protein antibody, FIP 2 antibody, FIP-2 antibody, FIP2 antibody, Glaucoma 1 open angle E (adult onset) antibody, Glaucoma 1 open angle E antibody, GLC1E antibody, HIP 7 antibody, HIP-7 antibody, HIP7 antibody, Huntingtin interacting protein 7 antibody, Huntingtin interacting protein HYPL antibody, Huntingtin interacting protein L antibody, Huntingtin yeast partner L antibody, Huntingtin-interacting protein 7 antibody, Huntingtin-interacting protein L antibody, HYPL antibody, Injury inducible protein I 55 antibody, NEMO related protein antibody, NEMO-related protein antibody, NRP antibody, Optic neuropathy inducing protein antibody, Optic neuropathy-inducing protein antibody, Optineurin antibody, OPTN antibody, OPTN_HUMAN antibody, TFIIIA IntP antibody, TFIIIA-IntP antibody, Transcription factor IIIA interacting protein antibody, Transcription factor IIIA-interacting protein antibody, Tumor necrosis factor alpha inducible cellular protein containing leucine zipper domains antibody

UniProt: Q96CV9

Pathways: M Phase