CPI-17 antibody

Catalog No. ABIN7138212

The Rabbit Polyclonal anti-CPI-17 antibody is suitable to detect CPI-17 in samples from Human. It has been validated for ELISA and IF.

Quick Overview for CPI-17 antibody (ABIN7138212)

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPI-17 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-CPI-17 Antibody

Purpose: PPP1R14A (Ab-38) Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Peptide sequence around aa.36~40 (R-V-T-V-K) derived from Human CPI17a.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CPI-17

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Alternative Name: PPP1R14A

Background:

Background: Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.

Hagerty L, et al. (2007) J Biol Chem. 2007, 282(7):4884-93
Seok YM, et al. (2008) J Pharmacol Exp Ther.
Niiro N et al. (2003) Biochem J. 2003 ,369(Pt 1):117-28

Aliases: 17 kDa PKC-potentiated inhibitory protein of PP1 antibody, 17-KDa protein antibody, 17 kDa PKC potentiated inhibitory protein of PP1 antibody, CPI 17 alpha antibody, CPI 17 antibody, CPI 17alpha antibody, CPI-17 antibody, CPI17 alpha antibody, CPI17 antibody, PKC potentiated inhibitory protein of PP1 antibody, PKC potentiated inhibitory protein of PP1, 17-KD antibody, PP14A_HUMAN antibody, PPP1INL antibody, Ppp1r14a antibody, Protein kinase C-potentiated inhibitor of protein phosphatase 1, 17-KD antibody, Protein kinase C-potentiated inhibitor protein of 17 kDa antibody, Protein phosphatase 1 antibody, Protein phosphatase 1 regulatory (inhibitor) subunit 14A antibody, Protein phosphatase 1 regulatory subunit 14A antibody, Regulatory subunit 14A antibody

UniProt: Q96A00