SUFUH antibody (pSer342)

Catalog No. ABIN7138564

This anti-SUFUH antibody is a Rabbit Polyclonal antibody detecting SUFUH in WB and ELISA. Suitable for Human.

Quick Overview for SUFUH antibody (pSer342) (ABIN7138564)

Target: SUFUH (Suppressor of Fused Homolog (SUFUH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUFUH antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SUFUH Antibody

Binding Specificity: pSer342

Cross-Reactivity: Human

Purification: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Peptide sequence around phosphorylation site of Serine 342 (A-P-S(p)-R-K) derived from Human Sufu.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SUFUH

Target: SUFUH (Suppressor of Fused Homolog (SUFUH))

Alternative Name: SUFU

Background:

Background: SUFU encodes a component of the Sonic hedgehog (SHH, MIM 600725)/Patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945, BCNS, MIM 109400, and GCPS, MIM 175700)

Zimmern P,et al.(2010) Neurourol Urodyn.29(5):715-8.
Wang C,et al. (2010) Development. 137(12):2001-9.
Rabasseda X.et al.(2010) Drug News Perspect.23(4):273-5.

Aliases: OTTHUMP00000020374 antibody, OTTHUMP00000020377 antibody, OTTHUMP00000020379 antibody, PRO1280 antibody, SU FU antibody, SU(F)U antibody, Su(fu) antibody, SUFU antibody, SUFU negative regulator of hedgehog signaling antibody, SUFU_HUMAN antibody, SUFUH antibody, SUFUXL antibody, Suppressor of Fused antibody, Suppressor of fused homolog (Drosophila) antibody, Suppressor of fused homolog antibody

UniProt: Q9UMX1

Pathways: Hedgehog Signaling, Tube Formation, Maintenance of Protein Location