ESR2 antibody (pSer105)

Catalog No. ABIN7138740

The Rabbit Polyclonal anti-ESR2 antibody has been validated for WB and ELISA. It is suitable to detect ESR2 in samples from Human.

Quick Overview for ESR2 antibody (pSer105) (ABIN7138740)

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ESR2 Antibody

Binding Specificity: pSer105

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine105(Q-R-S(p)-P-W) derived from Human Estrogen Receptor- beta.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ESR2

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Alternative Name: ESR2

Background:

Background:

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

Hamilton-Burke W, et al. (2010)Am J Pathol 177, 1079-86. St-Laurent V, Sanchez M, Charbonneau C, Tremblay A (2005) J Steroid Biochem Mol Biol 94, 23-37. Tremblay A, Tremblay GB, Labrie F, Gigure V (1999) Mol Cell 3, 513-9 .

Aliases: ER BETA antibody, ER-beta antibody, Erb antibody, ESR B antibody, ESR BETA antibody, ESR2 antibody, ESR2_HUMAN antibody, ESRB antibody, ESTRB antibody, estrogen nuclear receptor beta variant a antibody, estrogen nuclear receptor beta variant b antibody, estrogen receptor 2 (ER beta) antibody, Estrogen receptor 2 antibody, estrogen receptor beta 4 antibody, Estrogen receptor beta antibody, NR3A2 antibody, Nuclear receptor subfamily 3 group A member 2 antibody

UniProt: Q92731

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling