14-3-3 zeta antibody (pThr232)

Catalog No. ABIN7138893

The Rabbit Polyclonal anti-14-3-3 zeta antibody has been validated for WB and ELISA. It is suitable to detect 14-3-3 zeta in samples from Human.

Quick Overview for 14-3-3 zeta antibody (pThr232) (ABIN7138893)

Target: 14-3-3 zeta (YWHAZ)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 14-3-3 zeta antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-14-3-3 zeta Antibody

Binding Specificity: pThr232

Purpose: Phospho-YWHAZ (Thr232) Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine232(S-D-T(p)-Q-G) derived from Human 14-3-3 zeta/ delta .

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for 14-3-3 zeta

Target: 14-3-3 zeta (YWHAZ)

Alternative Name: YWHAZ

Background:

Background:

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

Sluchanko NN, et al. (2011) Arch Biochem Biophys 506, 24-34
Sluchanko NN, et al. (2008) Arch Biochem Biophys 477, 305-12
Clokie SJ, et al. (2005) FEBS J 272, 3767-76

Aliases: 14 3 3 delta antibody, 14 3 3 protein zeta/delta antibody, 14 3 3 protein/cytosolic phospholipase A2 antibody, 14 3 3 zeta antibody, 14-3-3 protein zeta/delta antibody, 1433Z_HUMAN antibody, Epididymis luminal protein 4 antibody, Epididymis secretory protein Li 3 antibody, HEL S 3 antibody, HEL4 antibody, KCIP-1 antibody, KCIP1 antibody, MGC111427 antibody, MGC126532 antibody, MGC138156 antibody, Phospholipase A2 antibody, Protein kinase C inhibitor protein 1 antibody, Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, delta polypeptide antibody, Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta antibody, Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta polypeptide antibody, Tyrosine 3/tryptophan 5 monooxygenase activation protein, zeta polypeptide antibody, YWHAD antibody, YWHAZ antibody

UniProt: P63104

Pathways: Apoptosis, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location