EGFR antibody (pTyr1197)

Catalog No. ABIN7138919

This Goat Polyclonal antibody specifically detects EGFR in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for EGFR antibody (pTyr1197) (ABIN7138919)

Target: EGFR (Epidermal Growth Factor Receptor (EGFR))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This EGFR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EGFR Antibody

Binding Specificity: pTyr1197

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen Affinity Purified

Immunogen: Peptide sequence around phosphorylation site of tyrosine 1197 (A-E-Y(p)-L-R) derived from Human EGFR.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for EGFR

Target: EGFR (Epidermal Growth Factor Receptor (EGFR))

Alternative Name: EGFR

Background:

Background: Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia

Corbalan-Garcia S, et al. (1996) Mol Cell Biolt, 16(10): 5674-5682
Kanner SB, et al. (1991) Mol Cell Biol, 11(2): 713-720
Wu TT, et al. (1998) Mol Biol Cell, 9(7): 1661-1674
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Aliases: Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody, Cell growth inhibiting protein 40 antibody, Cell proliferation inducing protein 61 antibody, EGF R antibody, EGFR antibody, EGFR_HUMAN antibody, Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) antibody, Epidermal growth factor receptor (erythroblastic leukemia viral (v erb b) oncogene homolog avian) antibody, Epidermal growth factor receptor antibody, erb-b2 receptor tyrosine kinase 1 antibody, ERBB antibody, ERBB1 antibody, Errp antibody, HER1 antibody, mENA antibody, NISBD2 antibody, Oncogen ERBB antibody, PIG61 antibody, Proto-oncogene c-ErbB-1 antibody, Receptor tyrosine protein kinase ErbB 1 antibody, Receptor tyrosine-protein kinase ErbB-1 antibody, SA7 antibody, Species antigen 7 antibody, Urogastrone antibody, v-erb-b Avian erythroblastic leukemia viral oncogen homolog antibody, wa2 antibody, Wa5 antibody

UniProt: P00533

Pathways: NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins