BCR antibody (pTyr177)
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- Target See all BCR Antibodies
- BCR (Breakpoint Cluster Region (BCR))
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Binding Specificity
- pTyr177
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BCR antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Mouse
- Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogen
- Peptide sequence around phosphorylation site of tyrosine 177 (P-F-Y(p)-V-N) derived from Human Bcr.
- Isotype
- IgG
- Top Product
- Discover our top product BCR Primary Antibody
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- Application Notes
- WB:1:500-1:1000, IHC:1:50-1:100,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- BCR (Breakpoint Cluster Region (BCR))
- Alternative Name
- BCR (BCR Products)
- Background
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Background: GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.
Sattler M, et al. Mol Cell Biol. 1999 Nov, 19(11): 7473-7480.
Li S et al. EMBO J. 2001 Dec 3, 20(23): 6793-6804.
Million RP, et,al. Mol Cell Biol. 2004 Jun, 24(11): 4685-4695.
Malcolm A. Meyn, et al. . Biol. Chem., Oct 2006, 281: 30907Aliases: ALL antibody, bcr antibody, BCR/ABL FUSION GENE, INCLUDED antibody, BCR/FGFR1 chimera protein antibody, BCR/FGFR1 FUSION GENE, INCLUDED antibody, BCR/PDGFRA FUSION GENE, INCLUDED antibody, BCR_HUMAN antibody, BCR1 antibody, Breakpoint cluster region antibody, Breakpoint cluster region protein antibody, CML antibody, D22S11 antibody, D22S662 antibody, FGFR1/BCR chimera protein antibody, PHL antibody, Renal carcinoma antigen NY-REN-26 antibody
- UniProt
- P11274
- Pathways
- Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
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