Ezrin antibody (pTyr353)
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- Target See all Ezrin (EZR) Antibodies
- Ezrin (EZR)
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Binding Specificity
- pTyr353
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Ezrin antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Mouse
- Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogen
- Peptide sequence around phosphorylation site of tyrosine 353 (Q-D-Y(p)-E-E) derived from Human EZRIN.
- Isotype
- IgG
- Top Product
- Discover our top product EZR Primary Antibody
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- Application Notes
- WB:1:500-1:1000, IHC:1:50-1:100,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Ezrin (EZR)
- Alternative Name
- EZR (EZR Products)
- Background
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Background:
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
Zhao H, et al. (2004) Proc Natl Acad Sci U S A101 (25): 9485-9490.
Wang Q, et al. (2003) J Biol Chem 278(48): 47731-47743.
Gautreau A, et al. (1999) Proc Natl Acad Sci U S A 96(13): 7300-7305.
Crepaldi T, et al. (1997) J Cell Biol 138(2): 423-34.
Aliases: Villin 2 ezrin antibody; CVIL antibody; CVL antibody; Cytovillin 2 antibody; Cytovillin antibody; DKFZp762H157 antibody; Epididymis secretory protein Li 105 antibody; EZR antibody; EZRI_HUMAN antibody; Ezrin antibody; FLJ26216 antibody; HEL S 105 antibody; MGC1584 antibody; p81 antibody; VIL 2 antibody; VIL2 antibody; Villin 2 (ezrin) antibody; Villin 2 antibody; Villin-2 antibody; Villin2 antibody
- UniProt
- P15311
- Pathways
- Maintenance of Protein Location
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