INPP5F antibody (AA 187-204)

Catalog No. ABIN7140040

This anti-INPP5F antibody is a Rabbit Polyclonal antibody detecting INPP5F in ELISA and IF. Suitable for Human.

Quick Overview for INPP5F antibody (AA 187-204) (ABIN7140040)

Target: INPP5F (Inositol Polyphosphate-5-Phosphatase F (INPP5F))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INPP5F antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-INPP5F Antibody

Binding Specificity: AA 187-204

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Peptide sequence from Human Phosphatidylinositide phosphatase SAC2 protein (187-204AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for INPP5F

Target: INPP5F (Inositol Polyphosphate-5-Phosphatase F (INPP5F))

Alternative Name: INPP5F

Background:

Background: Inositol 4-phosphatase which mainly acts on phosphatidylinositol 4-phosphate. May be functionally linked to OCRL, which converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol, for a sequential dephosphorylation of phosphatidylinositol 4,5-bisphosphate at the 5 and 4 position of inositol, thus playing an important role in the endocytic recycling (PubMed:25869669). Regulator of TF:TFRC and integrins recycling pathway, is also involved in cell migration mechanisms (PubMed:25869669). Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation (PubMed:17322895). Negatively regulates STAT3 signaling pathway through inhibition of STAT3 phosphorylation and translocation to the nucleus (PubMed:25476455). Functionally important modulator of cardiac myocyte size and of the cardiac response to stress (By similarity). May play a role as negative regulator of axon regeneration after central nervous system injuries (By similarity).

Aliases: INPP5F antibody, KIAA0966 antibody, SAC2 antibody, MSTP007 antibody, MSTP047 antibody, Phosphatidylinositide phosphatase SAC2 antibody, EC 3.1.3.25 antibody, Inositol polyphosphate 5-phosphatase F antibody, Sac domain-containing inositol phosphatase 2 antibody, Sac domain-containing phosphoinositide 4-phosphatase 2 antibody, hSAC2 antibody

UniProt: Q9Y2H2