Znf423 antibody (AA 39-57) (Biotin)

Catalog No. ABIN7140240

The Rabbit Polyclonal anti-Znf423 antibody has been validated for ELISA. It is suitable to detect Znf423 in samples from Human.

Quick Overview for Znf423 antibody (AA 39-57) (Biotin) (ABIN7140240)

Target: Znf423 (Zinc Finger Protein 423 (Znf423))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Znf423 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-Znf423 Antibody (Biotin)

Binding Specificity: AA 39-57

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Peptide sequence from Human Zinc finger protein 423 protein (39-57AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Znf423

Target: Znf423 (Zinc Finger Protein 423 (Znf423))

Alternative Name: ZNF423

Background:

Background: Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation, this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.

Aliases: Early B cell factor associated zinc finger protein antibody, Ebfaz antibody, hOAZ antibody, JBTS19 antibody, KIAA0760 antibody, NPHP14 antibody, Nur12 antibody, OAZ antibody, OLF 1/EBF associated zinc finger antibody, OLF1/EBF associated zinc finger protein antibody, Olf1/EBF-associated zinc finger protein antibody, Roaz antibody, Smad and Olf interacting zinc finger protein antibody, Smad- and Olf-interacting zinc finger protein antibody, Zfp104 antibody, ZFP423 antibody, zinc finger protein 423, mouse, homolog of antibody, Zinc finger protein 423 antibody, ZN423_HUMAN antibody, ZNF423 antibody, ZNF423 zinc finger protein 423 antibody

UniProt: Q2M1K9