BRAP antibody

Catalog No. ABIN7140299

This Mouse Monoclonal antibody specifically detects BRAP in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for BRAP antibody (ABIN7140299)

Target: BRAP (BRCA1 Associated Protein (BRAP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BRAP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BRAP Antibody

Purpose: BRAP Monoclonal Antibody

Purification: Affinity purified

Immunogen: Purified recombinant human BRAP protein fragments expressed in E.coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified mouse monoclonal antibody in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BRAP

Target: BRAP (BRCA1 Associated Protein (BRAP))

Alternative Name: BRAP

Background:

Background: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.

Aliases: 3010002G07Rik, BRAP2, BRCA1 associated protein, EC 6.3.2., Galectin 2 binding protein, IMP, Impedes mitogenic signal propagation, Renal carcinoma antigen NY REN 63, RING finger protein 52, RNF52, zgc:92894.

UniProt: Q7Z569