Crk antibody

Catalog No. ABIN7140311

This Mouse Monoclonal antibody specifically detects Crk in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Crk antibody (ABIN7140311)

Target: Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Crk antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Crk Antibody

Cross-Reactivity: Dog, Human, Mouse, Rabbit

Purification: Affinity purified

Immunogen: Purified recombinant human CRK protein fragments expressed in E.coli.

Isotype: IgG2b

Application Details

Application Notes: Recommended dilution:WB:1:500-1:5000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine ( pH 7.4, 150 mM NaCl) with 0.2 % sodium azide, 50 %,glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Crk

Target: Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

Alternative Name: CRK

Background:

Background: The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner.

Aliases: p38, CRKII

UniProt: P46108

Pathways: Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor