ICAM1 antibody (C-Term)

Catalog No. ABIN7140329

This Mouse Monoclonal antibody specifically detects ICAM1 in WB, ELISA and ICC. It exhibits reactivity toward Human.

Quick Overview for ICAM1 antibody (C-Term) (ABIN7140329)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ICAM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Product Details anti-ICAM1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: Affinity purified

Immunogen: Purified recombinant human ICAM1(C-terminus) protein fragments expressed in E.coli.

Isotype: IgG2b

Application Details

Application Notes: Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified mouse monoclonal in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Alternative Name: ICAM1

Background:

Background: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

Aliases: BB 2, BB2, CD 54, CD_antigen=CD54, CD54, Cell surface glycoprotein P3.58, Human rhinovirus receptor, ICAM 1, ICAM-1, ICAM1, ICAM1_HUMAN, Intercellular adhesion molecule 1, Major group rhinovirus receptor, MALA 2, MALA2, MyD 10, MyD10, P3.58

UniProt: P05362

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling