THIO (AA 1-369) antibody (HRP)

Catalog No. ABIN7140674

This Rabbit Polyclonal antibody specifically detects THIO in ELISA. It exhibits reactivity toward Bacillus subtilis.

Quick Overview for THIO (AA 1-369) antibody (HRP) (ABIN7140674)

Target: THIO

Reactivity: Bacillus subtilis

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: ELISA

Product Details

Binding Specificity: AA 1-369

Purpose: thiO Antibody, HRP conjugated

Cross-Reactivity: Bacillus subtilis

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Bacillus subtilis Glycine oxidase protein (1-369AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: THIO

Background:

Background: Catalyzes the FAD-dependent oxidative deamination of various amines and D-amino acids to yield the corresponding alpha-keto acids, ammonia/amine, and hydrogen peroxide. Oxidizes sarcosine (N-methylglycine), N-ethylglycine and glycine. Can also oxidize the herbicide glyphosate (N-phosphonomethylglycine). Displays lower activities on D-alanine, D-valine, D-proline and D-methionine. Does not act on L-amino acids and other D-amino acids. Is essential for thiamine biosynthesis since the oxidation of glycine catalyzed by ThiO generates the glycine imine intermediate (dehydroglycine) required for the biosynthesis of the thiazole ring of thiamine pyrophosphate.

Aliases: thiO antibody, goxB antibody, yjbR antibody, BSU11670Glycine oxidase antibody, GO antibody, EC 1.4.3.19 antibody

UniProt: O31616