LOC105923162 antibody (AA 1-136)
Quick Overview for LOC105923162 antibody (AA 1-136) (ABIN7140904)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-136
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Cross-Reactivity
- Malayan pit viper (Calloselasma rhodostoma)
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit alpha protein (1-136AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: WB:1:500-1:5000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- LOC105923162 (Lactose-Binding Lectin l-2-Like (LOC105923162))
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Alternative Name
- Snaclec rhodocytin subunit alpha
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Background
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Background: Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial.
Aliases: antibody, Snaclec rhodocytin subunit alpha antibody, Aggretin alpha chain antibody, Rhodoaggretin subunit alpha antibody
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UniProt
- Q9I841
Target
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