BotD (AA 1-442) antibody
Quick Overview for BotD (AA 1-442) antibody (ABIN7141060)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-442
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Purpose
- botD Antibody
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Purification
- Protein G purified
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Purity
- >95 %
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Immunogen
- Recombinant Clostridium botulinum Botulinum neurotoxin type D protein (1-442AA)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BotD
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Background
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Background: Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves the \'60-Lys-|-Leu-61\' bond of synaptobrevins-1 and -2.
Aliases: botD antibody, Botulinum neurotoxin type D antibody, BoNT/D antibody, Bontoxilysin-D) [Cleaved into: Botulinum neurotoxin D light chain antibody, LC antibody, EC 3.4.24.69), Botulinum neurotoxin D heavy chain antibody, HC)] antibody
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UniProt
- P19321
Target
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