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BotD (AA 1-442) antibody

The Rabbit Polyclonal anti-BotD antibody (ABIN7141060) specifically detects BotD in ELISA. The antibody is reactive with Clostridium botulinum samples.
Catalog No. ABIN7141060
$394.68
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Quick Overview for BotD (AA 1-442) antibody (ABIN7141060)

Target

BotD

Reactivity

Clostridium botulinum

Host

  • 3
  • 1
Rabbit

Clonality

  • 3
  • 1
Polyclonal

Conjugate

  • 1
  • 1
  • 1
  • 1
Un-conjugated

Application

  • 3
  • 1
ELISA
  • Binding Specificity

    AA 1-442

    Purpose

    botD Antibody

    Purification

    Protein G purified

    Purity

    >95 %

    Immunogen

    Recombinant Clostridium botulinum Botulinum neurotoxin type D protein (1-442AA)

    Isotype

    IgG
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    BotD

    Background

    Background: Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves the \'60-Lys-|-Leu-61\' bond of synaptobrevins-1 and -2.

    Aliases: botD antibody, Botulinum neurotoxin type D antibody, BoNT/D antibody, Bontoxilysin-D) [Cleaved into: Botulinum neurotoxin D light chain antibody, LC antibody, EC 3.4.24.69), Botulinum neurotoxin D heavy chain antibody, HC)] antibody

    UniProt

    P19321
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