BotF (AA 1-436) antibody (Biotin)

Catalog No. ABIN7141065

The Rabbit Polyclonal anti- antibody has been validated for ELISA. It is suitable to detect in samples from Clostridium botulinum.

Quick Overview for BotF (AA 1-436) antibody (Biotin) (ABIN7141065)

Target: BotF

Reactivity: Clostridium botulinum

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: ELISA

Product Details

Binding Specificity: AA 1-436

Cross-Reactivity: Clostridium botulinum

Purification: >95%, Protein G purified

Immunogen: Recombinant Clostridium botulinum Botulinum neurotoxin type F protein (1-436AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: BotF

Background:

Background: Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the \'58-Gln-|-Lys-59\' bond of synaptobrevins-1 and -2.

Aliases: botFBotulinum neurotoxin type F antibody, BoNT/F antibody, Bontoxilysin-F) [Cleaved into: Botulinum neurotoxin F light chain antibody, LC antibody, EC 3.4.24.69), Botulinum neurotoxin F heavy chain antibody, HC)] antibody

UniProt: P30996