Perfringolysin O (Pfo) (AA 29-500) antibody (Biotin)

Catalog No. ABIN7141089

The Rabbit Polyclonal anti-Perfringolysin O (Pfo) antibody is suitable to detect Perfringolysin O (Pfo) in samples from Clostridium perfringens. It has been validated for ELISA.

Quick Overview for Perfringolysin O (Pfo) (AA 29-500) antibody (Biotin) (ABIN7141089)

Target: Perfringolysin O (Pfo)

Reactivity: Clostridium perfringens

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: ELISA

Product Details

Binding Specificity: AA 29-500

Purpose: pfo Antibody, Biotin conjugated

Cross-Reactivity: Clostridium perfringens

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Clostridium perfringens Perfringolysin O protein (29-500AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Perfringolysin O (Pfo)

Alternative Name: pfo

Background:

Background: Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein assembles into a pre-pore complex. A conformation change leads to insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host cell membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation.

Aliases: pfo antibody, pfoA antibody, pfoR antibody, CPE0163 antibody, Perfringolysin O antibody, Theta-toxin antibody, Thiol-activated cytolysin antibody

UniProt: P0C2E9