CYP7B1 antibody (AA 312-430)

Catalog No. ABIN7142186

This Rabbit Polyclonal antibody specifically detects CYP7B1 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for CYP7B1 antibody (AA 312-430) (ABIN7142186)

Target: CYP7B1 (Cytochrome P450, Family 7, Subfamily B, Polypeptide 1 (CYP7B1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP7B1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-CYP7B1 Antibody

Binding Specificity: AA 312-430

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human 25-hydroxycholesterol 7-alpha-hydroxylase protein (312-430AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CYP7B1

Target: CYP7B1 (Cytochrome P450, Family 7, Subfamily B, Polypeptide 1 (CYP7B1))

Alternative Name: CYP7B1

Background:

Background: Oxysterol 7alpha-hydroxylase that mediates formation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) from 25-hydroxycholesterol (PubMed:10588945). Plays a key role in cell positioning and movement in lymphoid tissues: 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells (By similarity).

Aliases: 25 hydroxycholesterol 7 alpha hydroxylase antibody, 25-hydroxycholesterol 7-alpha-hydroxylase antibody, CP7B antibody, CP7B1_HUMAN antibody, Cyp7b1 antibody, Cytochrome P450 7B1 antibody, Cytochrome P450 family 7 subfamily B polypeptide 1 antibody, Cytochrome P450 subfamily VIIB polypeptide 1 antibody, Oxysterol 7-alpha-hydroxylase antibody, Oxysterol 7alpha hydroxylase antibody

UniProt: O75881

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Intracellular Steroid Hormone Receptor Signaling