CYP7B1 antibody (AA 200-300)

Catalog No. ABIN7266660

The Rabbit Polyclonal anti-CYP7B1 antibody (ABIN7266660) specifically detects CYP7B1 in WB. The antibody is reactive with Human samples.

Quick Overview for CYP7B1 antibody (AA 200-300) (ABIN7266660)

Target: CYP7B1 (Cytochrome P450, Family 7, Subfamily B, Polypeptide 1 (CYP7B1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP7B1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CYP7B1 Antibody

Binding Specificity: AA 200-300

Purpose: CYP7B1 Rabbit pAb

Sequence: VIVCDNNKFI SELRDDFLKF DDKFAYLVSN IPIELLGNVK SIREKIIKCF SSEKLAKMQG WSEVFQSRQD VLEKYYVHED LEIGAHHLGF LWASVANTIP T

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human CYP7B1 (NP_004811.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CYP7B1

Target: CYP7B1 (Cytochrome P450, Family 7, Subfamily B, Polypeptide 1 (CYP7B1))

Alternative Name: CYP7B1

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.,CYP7B1,CBAS3,CP7B,SPG5A,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Heart,Cardiac metabolism,Lipids,CYP7B1

Molecular Weight: 58kDa

Gene ID: 9420

UniProt: O75881

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Intracellular Steroid Hormone Receptor Signaling