Serotonin Receptor 1A antibody (AA 230-334) (HRP)

Catalog No. ABIN7142617

This anti-Serotonin Receptor 1A antibody is a Rabbit Polyclonal antibody detecting Serotonin Receptor 1A in ELISA. Suitable for Human.

Quick Overview for Serotonin Receptor 1A antibody (AA 230-334) (HRP) (ABIN7142617)

Target: Serotonin Receptor 1A (HTR1A)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 1A antibody is conjugated to HRP

Application: ELISA

Product Details anti-Serotonin Receptor 1A Antibody (HRP)

Binding Specificity: AA 230-334

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human 5-hydroxytryptamine receptor 1A protein (230-334AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Serotonin Receptor 1A

Target: Serotonin Receptor 1A (HTR1A)

Alternative Name: HTR1A

Background:

Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.

Aliases: 5 HT 1A antibody, 5 HT receptor 1A antibody, 5 HT1A antibody, 5 HT1A receptor antibody, 5 hydroxytryptamine (serotonin) receptor 1A antibody, 5 hydroxytryptamine (serotonin) receptor 1A G protein coupled antibody, 5 hydroxytryptamine receptor 1A antibody, 5-HT-1A antibody, 5-HT1A antibody, 5-hydroxytryptamine receptor 1A antibody, 5HT 1A antibody, 5HT 1A receptor antibody, 5HT receptor 1A antibody, 5HT1a antibody, 5HT1A_HUMAN antibody, ADRB2RL1 antibody, ADRBRL1 antibody, G 21 antibody, G protein coupled receptor antibody, G-21 antibody, Gpcr 18 antibody, Gpcr18 antibody, Guanine nucleotide binding regulatory protein-coupled receptor antibody, Htr1a antibody, PFMCD antibody, Serotonin 1A receptor antibody, Serotonin 5HT1A receptor antibody, Serotonin receptor 1A antibody

UniProt: P08908

Pathways: JAK-STAT Signaling, Synaptic Membrane, Feeding Behaviour