TRIP4 antibody (AA 360-535)

Catalog No. ABIN7143158

This Rabbit Polyclonal antibody specifically detects TRIP4 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for TRIP4 antibody (AA 360-535) (ABIN7143158)

Target: TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TRIP4 Antibody

Binding Specificity: AA 360-535

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Activating signal cointegrator 1 protein (360-535AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TRIP4

Target: TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))

Alternative Name: TRIP4

Background:

Background: Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation (PubMed:10454579, PubMed:25219498). Also involved in androgen receptor transactivation (By similarity). Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B (PubMed:12077347). May play a role in the development of neuromuscular junction (PubMed:26924529).

Aliases: Activating signal cointegrator 1 antibody, ASC 1 antibody, ASC-1 antibody, HsT17391 antibody, Thyroid hormone receptor interactor 4 antibody, Thyroid receptor interacting protein 4 antibody, Thyroid receptor-interacting protein 4 antibody, TR-interacting protein 4 antibody, TRIP 4 antibody, TRIP-4 antibody, Trip4 antibody, TRIP4_HUMAN antibody, ZC2HC5 antibody, Zinc finger C2HC5 type antibody

UniProt: Q15650