ACOT8 antibody (AA 1-200) (Biotin)

Catalog No. ABIN7143239

This Rabbit Polyclonal antibody specifically detects ACOT8 in ELISA. It exhibits reactivity toward Human.

Quick Overview for ACOT8 antibody (AA 1-200) (Biotin) (ABIN7143239)

Target: ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACOT8 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-ACOT8 Antibody (Biotin)

Binding Specificity: AA 1-200

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Acyl-coenzyme A thioesterase 8 protein (1-200AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ACOT8

Target: ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))

Alternative Name: ACOT8

Background:

Background: Acyl-coenzyme A (acyl-CoA) thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed: 9299485, PubMed: 9153233, PubMed: 15194431). Competes with bile acid CoA: amino acid N-acyltransferase (BAAT) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (C2 to C20) (PubMed: 9299485, PubMed: 9153233). Inactive towards substrates with more than C20 aliphatic chains (PubMed: 9153233). Involved in the metabolic regulation of peroxisome proliferation (PubMed: 15194431).

Aliases: ACOT8 antibody, ACTEIII antibody, PTE1 antibody, Acyl-coenzyme A thioesterase 8 antibody, Acyl-CoA thioesterase 8 antibody, EC 3.1.2.1 antibody, EC 3.1.2.11 antibody, EC 3.1.2.2 antibody, EC 3.1.2.3 antibody, EC 3.1.2.5 antibody, Choloyl-coenzyme A thioesterase antibody, EC 3.1.2.27 antibody, HIV-Nef-associated acyl-CoA thioesterase antibody, Peroxisomal acyl-CoA thioesterase 2 antibody, PTE-2 antibody, Peroxisomal acyl-coenzyme A thioester hydrolase 1 antibody, PTE-1 antibody, Peroxisomal long-chain acyl-CoA thioesterase 1 antibody, Thioesterase II antibody, hACTE-III antibody, hACTEIII antibody, hTE antibody

UniProt: O14734

Pathways: Monocarboxylic Acid Catabolic Process