Crk antibody (AA 40-196) (Biotin)

Catalog No. ABIN7143273

The Rabbit Polyclonal anti-Crk antibody has been validated for ELISA. It is suitable to detect Crk in samples from Human.

Quick Overview for Crk antibody (AA 40-196) (Biotin) (ABIN7143273)

Target: Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Crk antibody is conjugated to Biotin

Application: ELISA

Product Details anti-Crk Antibody (Biotin)

Binding Specificity: AA 40-196

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Adapter molecule crk protein (40-196AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Crk

Target: Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

Alternative Name: CRK

Background:

Background: Isoform Crk-II: Regulates cell adhesion, spreading and migration. Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Aliases: Adapter molecule crk antibody, Avian sarcoma virus CT10 (v crk) oncogene homolog antibody, CRK antibody, CRK isoform 2 antibody, CRK isoform II antibody, CRK_HUMAN antibody, CRKII antibody, FLJ38130 antibody, OTTHUMP00000115366 antibody, OTTHUMP00000198330 antibody, p38 antibody, Proto oncogene C crk antibody, Proto-oncogene C-crk antibody, v crk avian sarcoma virus CT10 oncogene homolog antibody, v crk sarcoma virus CT10 oncogene homolog antibody, v crk sarcoma virus CT10 oncogene homolog (avian) antibody

UniProt: P46108

Pathways: Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor