ADCY1 antibody (AA 897-1136) (FITC)

Catalog No. ABIN7143326

This Rabbit Polyclonal antibody specifically detects ADCY1 in . It exhibits reactivity toward Human.

Quick Overview for ADCY1 antibody (AA 897-1136) (FITC) (ABIN7143326)

Target: ADCY1 (Adenylate Cyclase 1 (Brain) (ADCY1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY1 antibody is conjugated to FITC

Application: Please inquire

Product Details anti-ADCY1 Antibody (FITC)

Binding Specificity: AA 897-1136

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Adenylate cyclase type 10 protein (897-1136AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ADCY1

Target: ADCY1 (Adenylate Cyclase 1 (Brain) (ADCY1))

Alternative Name: ADCY1

Background:

Background: Catalyzes the formation of the signaling molecule cAMP (PubMed:12609998, PubMed:15659711, PubMed:24616449, PubMed:25040695, PubMed:24567411). May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels (PubMed:15659711, PubMed:17591988). Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization (By similarity). Involved in ciliary beat regulation (PubMed:17591988).

Aliases: ADCY10 antibody, SAC antibody, Adenylate cyclase type 10 antibody, EC 4.6.1.1 antibody, AH-related protein antibody, Adenylate cyclase homolog antibody, Germ cell soluble adenylyl cyclase antibody, hsAC antibody, sAC antibody, Testicular soluble adenylyl cyclase antibody

UniProt: Q96PN6

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma