AKR1C1 antibody (AA 219-323) (Biotin)

Catalog No. ABIN7143687

The Rabbit Polyclonal anti-AKR1C1 antibody has been validated for ELISA. It is suitable to detect AKR1C1 in samples from Human.

Quick Overview for AKR1C1 antibody (AA 219-323) (Biotin) (ABIN7143687)

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR1C1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-AKR1C1 Antibody (Biotin)

Binding Specificity: AA 219-323

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Aldo-keto reductase family 1 member C1 protein (219-323AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AKR1C1

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Alternative Name: AKR1C1

Background:

Background: Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.

Aliases: 2-dihydrobenzene-1 antibody, 2-diol dehydrogenase antibody, 20 alpha (3 alpha) hydroxysteroid dehydrogenase antibody, 20 ALPHA HSD antibody, 20 alpha hydroxysteroid dehydrogenase antibody, 20-alpha-HSD antibody, 20-alpha-hydroxysteroid dehydrogenase antibody, 20ALPHAHSD antibody, 2ALPHAHSD antibody, AK1C1 antibody, AK1C1_HUMAN antibody, AKR1C1 antibody, Aldo keto reductase family 1 member C1 antibody, aldo-keto reductase C antibody, Aldo-keto reductase family 1 member C1 antibody, Aldo-keto reductase family, 1 member 1 antibody, C9 antibody, Chlordecone reductase homolog antibody, Chlordecone reductase homolog HAKRC antibody, DD1 antibody, DD1/DD2 antibody, DDH antibody, DDH1 antibody, Dihydrodiol dehydrogenase 1 antibody, Dihydrodiol dehydrogenase 1/2 antibody, dihydrodiol dehydrogenase 1, 20-alpha (3-alpha)-hydroxysteroid dehydrogenase antibody, dihydrodiol dehydrogenase isoform DD1 antibody, Dihydrodiol dehydrogenase, type 1 antibody, H37 antibody, HAKRC antibody, HBAB antibody, Hepatic dihydrodiol dehydrogenase antibody, High affinity hepatic bile acid-binding protein antibody, High-affinity hepatic bile acid-binding protein antibody, Indanol dehydrogenase antibody, MBAB antibody, MGC8954 antibody, Trans-1 antibody, Trans-1,2 dihydrobenzene 1,2 diol dehydrogenase antibody, Type II 3 alpha hydroxysteroid dehydrogenase antibody

UniProt: Q04828

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process