Ankyrin G antibody (AA 3540-3719)
Quick Overview for Ankyrin G antibody (AA 3540-3719) (ABIN7144251)
Target
See all Ankyrin G (ANK3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 3540-3719
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Ankyrin-3 protein (3540-3719AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Ankyrin G (ANK3) (Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))
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Alternative Name
- ANK3
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Background
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Background: In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments. Regulates KCNA1 channel activity in function of dietary Mg(2+) levels, and thereby contributes to the regulation of renal Mg(2+) reabsorption (PubMed:23903368).
Aliases: ANK-3 antibody, ANK3 antibody, ANK3_HUMAN antibody, ankyrin 3 (G) antibody, Ankyrin 3, node of Ranvier (ankyrin G) antibody, Ankyrin 3, node of Ranvier antibody, Ankyrin G antibody, Ankyrin G119 antibody, Ankyrin-3 antibody, Ankyrin-G antibody, brain specific ankyrin G antibody, CHANK3 antibody, FLJ45464 antibody, OTTHUMP00000217458 antibody, OTTHUMP00000217575 antibody, RP11 369L1.1 antibody
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UniProt
- Q12955
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Pathways
- Synaptic Membrane, Maintenance of Protein Location, Skeletal Muscle Fiber Development
Target
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