APOC1 antibody (AA 35-48)

Catalog No. ABIN7144415

This Rabbit Polyclonal antibody specifically detects APOC1 in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for APOC1 antibody (AA 35-48) (ABIN7144415)

Target: APOC1 (Apolipoprotein C-I (APOC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOC1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-APOC1 Antibody

Binding Specificity: AA 35-48

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Apolipoprotein C-I protein (35-48aa)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for APOC1

Target: APOC1 (Apolipoprotein C-I (APOC1))

Alternative Name: APOC1

Background:

Background: Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10 % of the protein of the VLDL and 2 % of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.

Aliases: Apolipoprotein C-I (Apo-CI) (ApoC-I) (Apolipoprotein C1) [Cleaved into: Truncated apolipoprotein C-I], APOC1

UniProt: P02654

Pathways: Apoptosis