ALOX15B antibody (AA 1-676) (Biotin)

Catalog No. ABIN7144535

This Rabbit Polyclonal antibody specifically detects ALOX15B in ELISA. It exhibits reactivity toward Human.

Quick Overview for ALOX15B antibody (AA 1-676) (Biotin) (ABIN7144535)

Target: ALOX15B (Arachidonate 15-Lipoxygenase B (ALOX15B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALOX15B antibody is conjugated to Biotin

Application: ELISA

Product Details anti-ALOX15B Antibody (Biotin)

Binding Specificity: AA 1-676

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Arachidonate 15-lipoxygenase B protein (1-676AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ALOX15B

Target: ALOX15B (Arachidonate 15-Lipoxygenase B (ALOX15B))

Alternative Name: ALOX15B

Background:

Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells.

Aliases: 15 Lipoxygenase 2 antibody, 15 LO 2 antibody, 15 LOX 2 antibody, 15-lipoxygenase 2 antibody, 15-LOX-2 antibody, 15-LOX-B antibody, Alox15b antibody, Arachidonate 15 lipoxygenase second type antibody, Arachidonate 15 lipoxygenase type II antibody, Arachidonate 15-lipoxygenase B antibody, Arachidonate 15-lipoxygenase type II antibody, LX15B_HUMAN antibody

UniProt: O15296