ARPIN antibody (AA 1-226)
Quick Overview for ARPIN antibody (AA 1-226) (ABIN7144631)
Target
See all ARPIN AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-226
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Cross-Reactivity
- Human
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Arpin protein (1-226AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ARPIN
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Background
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Background: Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competetive with nucleation promoting factors. Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimulates actin polymerization through the WAVE complex. Involved in steering cell migration by controlling its directional persistence.
Aliases: 2610034B18Rik antibody, Actin related protein 2/3 complex inhibitor antibody, Arp2/3 inhibition protein antibody, ARPIN antibody, C15orf38 antibody, Chromosome 15 open reading frame 38 antibody, CO038_HUMAN antibody, Hypothetical protein LOC348110 antibody, MGC61550 antibody, RIKEN cDNA 2610034B18 antibody, UPF0552 protein C15orf38 antibody
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UniProt
- Q7Z6K5
Target
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