ASTL antibody (AA 38-337) (Biotin)

Catalog No. ABIN7144766

This Rabbit Polyclonal antibody specifically detects ASTL in ELISA. It exhibits reactivity toward Human.

Quick Overview for ASTL antibody (AA 38-337) (Biotin) (ABIN7144766)

Target: ASTL (Astacin-Like Metallo-Endopeptidase (M12 Family) (ASTL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASTL antibody is conjugated to Biotin

Application: ELISA

Product Details anti-ASTL Antibody (Biotin)

Binding Specificity: AA 38-337

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Astacin-like metalloendopeptidase protein (38-337AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ASTL

Target: ASTL (Astacin-Like Metallo-Endopeptidase (M12 Family) (ASTL))

Alternative Name: ASTL

Background:

Background: Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding.

Aliases: ASTLAstacin-like metalloendopeptidase antibody, EC 3.4.-.- antibody, Oocyte astacin antibody, Ovastacin antibody

UniProt: Q6HA08