Ataxin 1 antibody (AA 586-815)

Catalog No. ABIN7144783

This anti-Ataxin 1 antibody is a Rabbit Polyclonal antibody detecting Ataxin 1 in IHC and ELISA. Suitable for Human.

Quick Overview for Ataxin 1 antibody (AA 586-815) (ABIN7144783)

Target: Ataxin 1 (ATXN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ataxin 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-Ataxin 1 Antibody

Binding Specificity: AA 586-815

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Ataxin-1 protein (586-815AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Ataxin 1

Target: Ataxin 1 (ATXN1)

Alternative Name: ATXN1

Background:

Background: Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.

Aliases: alternative ataxin1 antibody, Ataxin-1 antibody, ATX1 antibody, ATX1_HUMAN antibody, Atxn1 antibody, D6S504E antibody, OTTHUMP00000016065 antibody, SCA1 antibody, Spinocerebellar ataxia type 1 protein antibody

UniProt: P54253

Pathways: Synaptic Membrane