ATPase Inhibitory Factor 1 antibody (AA 26-106)

Catalog No. ABIN7145048

This Rabbit Polyclonal antibody specifically detects ATPase Inhibitory Factor 1 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for ATPase Inhibitory Factor 1 antibody (AA 26-106) (ABIN7145048)

Target: ATPase Inhibitory Factor 1 (ATPIF1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATPase Inhibitory Factor 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-ATPase Inhibitory Factor 1 Antibody

Binding Specificity: AA 26-106

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human ATPase inhibitor, mitochondrial protein (26-106AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ATPase Inhibitory Factor 1

Target: ATPase Inhibitory Factor 1 (ATPIF1)

Alternative Name: ATPIF1

Background:

Background: Endogenous F1F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F1F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F1F(o)-ATP synthase enzyme acts as an ATP hydrolase. Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.

Aliases: ATIF1_HUMAN antibody, ATP synthase inhibitor protein antibody, ATPase inhibitor antibody, ATPase inhibitor mitochondrial antibody, ATPase inhibitor protein antibody, ATPase inhibitory factor 1 antibody, ATPI antibody, ATPIF 1 antibody, Atpif1 antibody, ATPIP antibody, IF(1) antibody, IF1 antibody, Inhibitor of F(1)F(o)-ATPase antibody, IP antibody, MGC1167 antibody, MGC8898 antibody, mitochondrial antibody

UniProt: Q9UII2