Corin antibody (AA 1-110)

Catalog No. ABIN7145063

This Rabbit Polyclonal antibody specifically detects Corin in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Corin antibody (AA 1-110) (ABIN7145063)

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Corin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-Corin Antibody

Binding Specificity: AA 1-110

Cross-Reactivity: Human, Rat

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Atrial natriuretic peptide-converting enzyme protein (1-110AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Corin

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Alternative Name: CORIN

Background:

Background: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide.

Aliases: activated protease fragment antibody, ATC 2 antibody, ATC2 antibody, Atrial natriuretic peptide-converting enzyme antibody, Atrial natriuteric peptide converting enzyme antibody, Corin antibody, Corin serine peptidase antibody, CORIN_HUMAN antibody, CRN antibody, Heart specific serine proteinase antibody, Heart specific serine proteinase ATC2 antibody, Heart-specific serine proteinase ATC2 antibody, MGC119742 antibody, Pro ANP convertase antibody, Pro ANP converting enzyme antibody, Pro-ANP-converting enzyme antibody, TMPRSS 10 antibody, TMPRSS10 antibody, Transmembrane protease serine 10 antibody

UniProt: Q9Y5Q5

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones