BMPR1B antibody (AA 14-126)

Catalog No. ABIN7145708

Product Details anti-BMPR1B Antibody

Target: BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Binding Specificity: AA 14-126

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMPR1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Bone morphogenetic protein receptor type-1B protein (14-126AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BMPR1B

Target: BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Alternative Name: BMPR1B (BMPR1B Products)

Background:

Background: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction.

Aliases: Activin receptor like kinase 6 antibody, Acvrlk6 antibody, ALK 6 antibody, ALK6 antibody, alk6tr antibody, BMP type-1B receptor antibody, BMPR IB antibody, BMPR-1B antibody, Bmpr1b antibody, BMPRIB antibody, BMR1B_HUMAN antibody, Bone morphogenetic protein receptor type 1B antibody, Bone morphogenetic protein receptor type IB antibody, Bone morphogenetic protein receptor type-1B antibody, BR 1b antibody, BR1b antibody, CDw 293 antibody, CDw293 antibody, CDw293 antigen antibody, CFK 43a antibody, CFK43a antibody, Serine/threonine receptor kinase antibody, zALK 6 antibody, zALK6 antibody

UniProt: O00238