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BMPR1B Products

(Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

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This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].

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Featured BMPR1B Categories

BMPR1B Antibodies

High quality antibodies with extensive validation data.

BMPR1B ELISA Kits

Reliable ELISA kits for a wide range of species.

BMPR1B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended BMPR1B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IF, IHC
Validations
  • (5)
Cat. No. ABIN7260047
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
  • (4)
Cat. No. ABIN7145708
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Human, Mouse
Application IHC (p), WB
Validations
  • (1)
  • (3)
Cat. No. ABIN2855400
Quantity 100 μL
Datasheet Datasheet

Recommended BMPR1B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954155
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4881803
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6384298
Quantity 96 tests
Datasheet Datasheet

Recommended BMPR1B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
Cat. No. ABIN1346785
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (2)
Cat. No. ABIN5569802
Quantity 5 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7194418
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our BMPR1B products

Tengroth, Arebro, Larsson, Bachert, Georén, Cardell: "Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps." in: Scientific reports, Vol. 8, Issue 1, pp. 1561, (2018) (PubMed).

Ferguson, Van Handel, Bay, Fiziev, Org, Lee, Shkhyan, Banks, Scheinberg, Wu, Saitta, Elphingstone, Larson, Riester, Pyle, Bernthal, Mikkola, Ernst, van Wijnen, Bonaguidi, Evseenko: "Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes." in: Nature communications, Vol. 9, Issue 1, pp. 3634, (2018) (PubMed).

Toofan, Busch, Morrison, OBrien, Jørgensen, Copland, Wheadon: "Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewal." in: Cell death & disease, Vol. 9, Issue 9, pp. 927, (2018) (PubMed).

Hegarty, Sullivan, OKeeffe: "Endocytosis contributes to BMP2-induced Smad signalling and neuronal growth." in: Neuroscience letters, Vol. 643, pp. 32-37, (2017) (PubMed).

Wang, He, Zhang, Shi, Dong, Pei, Zhu: "A Selective Cell Population From Dermis Strengthens Bone Regeneration." in: Stem cells translational medicine, (2016) (PubMed).

Chung, Gao, Jegga, Das: "Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a." in: Molecular and cellular endocrinology, Vol. 400, pp. 48-60, (2015) (PubMed).

Srikanth, Kim, Das, Kessler: "BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells." in: Molecular cancer research : MCR, Vol. 12, Issue 2, pp. 283-94, (2014) (PubMed).

He, Dong, Wang, Xu, Dai, Ma, Zhu: "Bone morphogenetic protein receptor IB as a marker for enrichment of osteogenic precursor-like cells in human dermis." in: Archives of dermatological research, Vol. 303, Issue 8, pp. 581-90, (2011) (PubMed).

Kan, Liu, McGuire, Berger, Awatramani, Dymecki, Kessler: "Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification." in: Stem cells (Dayton, Ohio), Vol. 27, Issue 1, pp. 150-6, (2009) (PubMed).

Nicholls, Harrison, Gilchrist, Farnworth, Stanton: "Growth differentiation factor 9 is a germ cell regulator of Sertoli cell function." in: Endocrinology, Vol. 150, Issue 5, pp. 2481-90, (2009) (PubMed).

Synonyms and alternative names related to BMPR1B

bone morphogenetic protein receptor type 1B (BMPR1B), bone morphogenetic protein receptor type 1B (bmpr1b), bone morphogenetic protein receptor, type IBb (bmpr1bb), bone morphogenetic protein receptor, type 1B (Bmpr1b), bone morphogenetic protein receptor, type IBa (bmpr1ba), bone morphogenetic protein receptor type 1B (Bmpr1b), Acvrlk6, AI385617, alk-6, ALK-6, ALK6, alk6, Alk6, alk6b, alk6tr, AV355320, BMP15, BMPR-1B, BMPR-IB, BMPR1B, bmpr1b, BMPRIB, BR1b, cdw293, CDw293, CFK-43a, FecB, RPK-1, SKR6, zALK-6, zgc:92220, zgc:172219

Protein level used designations for BMPR1B

  • BMP receptor IB
  • activin receptor-like kinase 6
  • bone morphogenetic protein receptor type-1B
  • bone morphogenetic protein receptor, type IB
  • bone morphogenetic protein receptor type IB,b
  • bone morphogenetic protein receptor type-1B-like
  • BMP type-1B receptor
  • serine/threonine-protein kinase receptor R6
  • alk6
  • bone morphogenetic protein receptor, type 1b
  • BMPR-1B
  • serine/threonine receptor kinase
  • bone morphogenetic protein receptor IB
  • bone morphogenetic protein binding serine/threonine kinase receptor
  • ALK-6
  • SKR6
  • receptor protein kinase
  • bone morphogenetic protein receptor 1B
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