BCAR1 antibody (AA 68-218) (Biotin)

Catalog No. ABIN7145767

This anti-BCAR1 antibody is a Rabbit Polyclonal antibody detecting BCAR1 in ELISA. Suitable for Human.

Quick Overview for BCAR1 antibody (AA 68-218) (Biotin) (ABIN7145767)

Target: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAR1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-BCAR1 Antibody (Biotin)

Binding Specificity: AA 68-218

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Breast cancer anti-estrogen resistance protein 1 protein (68-218AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BCAR1

Target: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Alternative Name: BCAR1

Background:

Background: Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.

Aliases: BCAR 1 antibody, Bcar1 antibody, BCAR1_HUMAN antibody, Breast cancer anti estrogen resistance 1 antibody, Breast cancer anti estrogen resistance 1 protein antibody, Breast cancer anti-estrogen resistance protein 1 antibody, CAS antibody, Cas scaffolding protein family member 1 antibody, CAS1 antibody, Cass1 antibody, Crk associated substrate antibody, Crk associated substrate p130Cas antibody, CRK-associated substrate antibody, CRKAS antibody, FLJ12176 antibody, FLJ45059 antibody, p130cas antibody

UniProt: P56945

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling