CD27 antibody (AA 229-312) (Biotin)

Catalog No. ABIN7146086

This Rabbit Polyclonal antibody specifically detects CD27 in ELISA. It exhibits reactivity toward Human.

Quick Overview for CD27 antibody (AA 229-312) (Biotin) (ABIN7146086)

Target: CD27 (CD27 Molecule (CD27))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD27 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-CD27 Antibody (Biotin)

Binding Specificity: AA 229-312

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human C-type lectin domain family 4 member K protein (229-312AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CD27

Target: CD27 (CD27 Molecule (CD27))

Alternative Name: CD27

Background:

Background: Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs), is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

Aliases: C type lectin domain family 4 member K antibody, C-type lectin domain family 4 member K antibody, CD 207 antibody, CD207 antibody, CD207 antigen antibody, CD207 antigen, langerin antibody, CD207 Molecule antibody, CLC4K_HUMAN antibody, CLEC 4K antibody, CLEC4K antibody, Langerhans cell specific c type lectin antibody, Langerin antibody, RGD1565913 antibody

UniProt: Q9UJ71

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints