C5AR1 antibody (AA 1-36) (Biotin)

Catalog No. ABIN7146171

The Rabbit Polyclonal anti-C5AR1 antibody has been validated for ELISA. It is suitable to detect C5AR1 in samples from Human.

Quick Overview for C5AR1 antibody (AA 1-36) (Biotin) (ABIN7146171)

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C5AR1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-C5AR1 Antibody (Biotin)

Binding Specificity: AA 1-36

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human C5a anaphylatoxin chemotactic receptor 1 protein (1-36AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for C5AR1

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Alternative Name: C5AR1

Background:

Background: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).

Aliases: ANAPHYLATOXIN RECEPTOR antibody, C5a anaphylatoxin chemotactic receptor antibody, C5a anaphylatoxin receptor antibody, C5A antibody, C5a ligand antibody, C5a-R antibody, C5aR antibody, C5AR_HUMAN antibody, c5ar1 antibody, C5R1 antibody, CD88 antibody, CD88 antigen antibody, Complement component 5 receptor 1 antibody, Complement component 5 receptor 2 antibody, Complement component 5a receptor 1 antibody

UniProt: P21730

Pathways: Complement System