Tescalcin antibody (AA 2-214) (FITC)

Catalog No. ABIN7146267

The Rabbit Polyclonal anti-Tescalcin antibody has been validated for . It is suitable to detect Tescalcin in samples from Human.

Quick Overview for Tescalcin antibody (AA 2-214) (FITC) (ABIN7146267)

Target: Tescalcin (TESC)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tescalcin antibody is conjugated to FITC

Application: Please inquire

Product Details anti-Tescalcin Antibody (FITC)

Binding Specificity: AA 2-214

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Calcineurin B homologous protein 3 protein (2-214AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Tescalcin

Target: Tescalcin (TESC)

Alternative Name: TESC

Background:

Background: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.

Aliases: TESC antibody, CHP3Calcineurin B homologous protein 3 antibody, Tescalcin antibody, TSC antibody

UniProt: Q96BS2

Pathways: Proton Transport