CAMKK2 antibody (AA 5-148)

Catalog No. ABIN7146424

This anti-CAMKK2 antibody is a Rabbit Polyclonal antibody detecting CAMKK2 in ELISA and IHC. Suitable for Human.

Quick Overview for CAMKK2 antibody (AA 5-148) (ABIN7146424)

Target: CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAMKK2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-CAMKK2 Antibody

Binding Specificity: AA 5-148

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Calcium/calmodulin-dependent protein kinase kinase 2 protein (5-148AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CAMKK2

Target: CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

Alternative Name: CAMKK2

Background:

Background: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals (By similarity). Seems to be involved in hippocampal activation of CREB1 (By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.

Aliases: Calcium/calmodulin dependent protein kinase beta antibody, Calcium/calmodulin dependent protein kinase kinase 2 antibody, Calcium/calmodulin dependent protein kinase kinase 2 beta antibody, Calcium/calmodulin dependent protein kinase kinase beta antibody, Calcium/calmodulin-dependent protein kinase kinase 2 antibody, Calcium/calmodulin-dependent protein kinase kinase beta antibody, CaM kinase kinase beta antibody, CaM KK beta antibody, CaM-kinase kinase 2 antibody, CaM-kinase kinase beta antibody, CaM-KK 2 antibody, CaM-KK beta antibody, CaMKK 2 antibody, CAMKK antibody, CaMKK beta antibody, CAMKK beta protein antibody, Camkk2 antibody, CAMKKB antibody, KKCC2_HUMAN antibody

UniProt: Q96RR4

Pathways: AMPK Signaling