Caldesmon antibody (AA 1-240)

Catalog No. ABIN7146462

The Rabbit Polyclonal anti-Caldesmon antibody has been validated for IHC and ELISA. It is suitable to detect Caldesmon in samples from Human.

Quick Overview for Caldesmon antibody (AA 1-240) (ABIN7146462)

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caldesmon antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-Caldesmon Antibody

Binding Specificity: AA 1-240

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Caldesmon protein (1-240AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Caldesmon

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Alternative Name: CALD1

Background:

Background: Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration.

Aliases: CAD antibody, CALD 1 antibody, CALD1 antibody, CALD1_HUMAN antibody, Caldesmon 1 antibody, Caldesmon 1 Isoform 1 antibody, Caldesmon 1 Isoform 2 antibody, Caldesmon 1 Isoform 3 antibody, Caldesmon 1 Isoform 4 antibody, Caldesmon 1 Isoform 5 antibody, Caldesmon antibody, Caldesmon1 antibody, CDM antibody, H CAD antibody, HCAD antibody, L CAD antibody, LCAD antibody, MGC21352 antibody, NAG22 antibody

UniProt: Q05682

Pathways: Myometrial Relaxation and Contraction