Calreticulin antibody (AA 18-415)

Catalog No. ABIN7146564

The Rabbit Polyclonal anti-Calreticulin antibody has been validated for WB, IHC, ELISA and IF. It is suitable to detect Calreticulin in samples from Human.

Quick Overview for Calreticulin antibody (AA 18-415) (ABIN7146564)

Target: Calreticulin (CALR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calreticulin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Calreticulin Antibody

Binding Specificity: AA 18-415

Cross-Reactivity: Human, Mouse, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Calreticulin protein (18-415AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Calreticulin

Target: Calreticulin (CALR)

Alternative Name: CALR

Background:

Background: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).

Aliases: Autoantigen RO antibody, CALR antibody, CALR protein antibody, CALR_HUMAN antibody, Calregulin antibody, Calreticulin antibody, cC1qR antibody, CRP55 antibody, CRT antibody, CRTC antibody, Endoplasmic reticulum resident protein 60 antibody, Epididymis secretory sperm binding protein Li 99n antibody, ERp60 antibody, FLJ26680 antibody, grp60 antibody, HACBP antibody, HEL S 99n antibody, RO antibody, Sicca syndrome antigen A (autoantigen Ro, calreticulin) antibody, Sicca syndrome antigen A antibody, SSA antibody

UniProt: P27797

Pathways: Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response