FLIP antibody (AA 1-250) (HRP)

Catalog No. ABIN7146904

This anti-FLIP antibody is a Rabbit Polyclonal antibody detecting FLIP in ELISA. Suitable for Human.

Quick Overview for FLIP antibody (AA 1-250) (HRP) (ABIN7146904)

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLIP antibody is conjugated to HRP

Application: ELISA

Product Details anti-FLIP Antibody (HRP)

Binding Specificity: AA 1-250

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human CASP8 and FADD-like apoptosis regulator protein (1-250AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FLIP

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Alternative Name: CFLAR

Background:

Background: Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.

Aliases: c FLIP antibody, c FLIPL antibody, c FLIPR antibody, c FLIPS antibody, c-FLIP antibody, c-FLIPL antibody, c-FLIPR antibody, c-FLIPS antibody, CASH antibody, CASP8 and FADD like apoptosis regulator antibody, CASP8 and FADD-like apoptosis regulator subunit p12 antibody, CASP8AP1 antibody, Caspase homolog antibody, Caspase like apoptosis regulatory protein antibody, Caspase related inducer of apoptosis antibody, Caspase-eight-related protein antibody, Caspase-like apoptosis regulatory protein antibody, Casper antibody, cellular flice inhibitory protein antibody, Cellular FLICE-like inhibitory protein antibody, CFLA antibody, Cflar antibody, CFLAR_HUMAN antibody, CLARP antibody, FADD like anti apoptotic molecule antibody, FADD-like antiapoptotic molecule 1 antibody, FLAME antibody, FLAME-1 antibody, FLAME1 antibody, FLIP antibody, I FLICE antibody, I-FLICE antibody, Inhibitor of FLICE antibody, MACH-related inducer of toxicity antibody, MRIT antibody, OTTHUMP00000163715 antibody, OTTHUMP00000206475 antibody, OTTHUMP00000206476 antibody, OTTHUMP00000206478 antibody, OTTHUMP00000206479 antibody, OTTHUMP00000206480 antibody, OTTHUMP00000206482 antibody, OTTHUMP00000207360 antibody, Usurpin antibody, Usurpin beta antibody

UniProt: O15519

Pathways: Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development