CNOT1 antibody (AA 595-744)
Quick Overview for CNOT1 antibody (AA 595-744) (ABIN7147093)
Target
See all CNOT1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 595-744
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human CCR4-NOT transcription complex subunit 10 protein (595-744AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: IHC:1:200-1:500,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CNOT1 (CCR4-NOT Transcription Complex, Subunit 1 (CNOT1))
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Alternative Name
- CNOT1
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Background
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Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex.
Aliases: CNOT10CCR4-NOT transcription complex subunit 10 antibody
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UniProt
- Q9H9A5
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Pathways
- Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Stem Cell Maintenance
Target
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